Effect of p-Hydroxyacetanilide on Liver Cancer Induction by /V-Hydroxy-7V-2-fluorenylacetamide


We explored, in rats, the conditions underlying the induction of liver tumors by ./V-hydroxy-./V-2-fluorenylacetamide (N-OH-FAA) in terms of the participation of an ultimate carcinogen in the form of the sulfate ester. Male rats were fed 2 dose levels, i.e., 0.0213%(0.89 mmole/kg) and 0.032%(1.34 mmoles/kg) of N-OH-FAA in the diet, with or without 0.89% (59… (More)


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