Effect of ozone treatment on reactive oxygen species and adenosine production during hepatic ischemia-reperfusion.

@article{Peralta2000EffectOO,
  title={Effect of ozone treatment on reactive oxygen species and adenosine production during hepatic ischemia-reperfusion.},
  author={Carmen Peralta and Carme Xaus and Ramon Bartrons and Olga Sonia Le{\'o}n and Emilio Gelp{\'i} and Joan Rosell{\'o}-Catafau},
  journal={Free radical research},
  year={2000},
  volume={33 5},
  pages={595-605}
}
This study investigates whether ozone could confer protection from hepatic ischemia reperfusion by modifying the accumulation of adenosine and xanthine during ischemia. A significant increase in both adenosine and xanthine accumulation was observed as a consequence of ATP degradation during hepatic ischemia. Adenosine exerts a protective effect on hepatic ischemia reperfusion injury since the elimination of endogenous adenosine accumulation with adenosine deaminase increased the hepatic injury… CONTINUE READING

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