Effect of oxytocin on the behavioral activity in the behavioral despair depression rat model.

@article{Yan2014EffectOO,
  title={Effect of oxytocin on the behavioral activity in the behavioral despair depression rat model.},
  author={Yuan Ji Yan and Yong-Liang Wang and Zhou Su and Yi Zhang and Shuang-Xi Guo and A Liu and Changhong Wang and Fang-Jie Sun and Jun Yang},
  journal={Neuropeptides},
  year={2014},
  volume={48 2},
  pages={83-9}
}
Oxytocin (OXT), a nonapeptide posterior hormone of the pituitary, is mainly synthesized and secreted in the hypothalamic paraventricular nucleus (PVN) and supraoptic nucleus (SON). The present study was to investigate in which level, brain or periphery, OXT effecting on the behavioral activity in the behavioral despair depression rat model. The results showed that (1) either the forced swimming or the tail suspension significantly increased OXT concentration in the brain (PVN, SON, frontal… CONTINUE READING
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