Effect of ouabain on O2 supply/demand in normal and ischemic heart


The effect of ouabain (15 μg/kg) on subepicardial and subendocardial blood flow, oxygenation, and small-vessel blood content was studied in anesthetized open-chest rabbits with hearts subjected to acute coronary occlusion. 10 minutes after occlusion, blood flow was 48% lower than in the control region. Ouabain lowered blood flow significantly in the non… (More)
DOI: 10.1007/BF01907946


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