Effect of orotic acid on TGF-beta 1-induced growth inhibition of L1210 leukemic cells.

Abstract

UNLABELLED Transforming growth factor-beta 1 (TGF-beta 1) exerted growth-inhibitory effect on L1210 leukemic cell line, manifested by the decrease in viable and increase in dead cells. The cell death evoked by TGF-beta 1 was both necrotic and apoptotic, quantified by the trypan blue exclusion method and apoptotic index, respectively. The induction of… (More)

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@article{Grzelkowska1995EffectOO, title={Effect of orotic acid on TGF-beta 1-induced growth inhibition of L1210 leukemic cells.}, author={K. Grzelkowska and Tomasz Motyl and Ewa Malicka and Jerzy Ostrowski and Lech Trzeciak and Marcin Filipecki}, journal={International journal of hematology}, year={1995}, volume={61 1}, pages={23-33} }