Effect of organic solvent exposure on chronic kidney disease progression: the GN-PROGRESS cohort study.

@article{Jacob2007EffectOO,
  title={Effect of organic solvent exposure on chronic kidney disease progression: the GN-PROGRESS cohort study.},
  author={Sophie Jacob and Michel H{\'e}ry and Jean-Claude Protois and J{\'e}r{\^o}me A Rossert and B{\'e}n{\'e}dicte Stengel},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2007},
  volume={18 1},
  pages={
          274-81
        }
}
It has been suggested that solvent exposure may have a role in the progression of glomerulonephritis (GN) to ESRD, but this has never been tested with an appropriate cohort study design. A total of 338 non-ESRD patients with a first biopsy for primary GN between 1994 and 2001 were included: 194 IgA nephropathies (IgAN), 75 membranous nephropathies (MN), and 69 FSGS. ESRD, defined as an estimated GFR <15 ml/min per 1.73 m2 or dialysis, was registered during a mean follow-up period of 5 yr… CONTINUE READING
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