Effect of orally administered glutathione on glutathione levels in some organs of rats: role of specific transporters.

@article{Favilli1997EffectOO,
  title={Effect of orally administered glutathione on glutathione levels in some organs of rats: role of specific transporters.},
  author={Fabio Favilli and Patrizia Marraccini and Teresa Iantomasi and Maria Teresa Vincenzini},
  journal={The British journal of nutrition},
  year={1997},
  volume={78 2},
  pages={293-300}
}
The present study reports data on absorption of orally administered glutathione (GSH) in rat jejunum and in other organs, and the possible role of specific transport systems of GSH and gamma-glutamyltranspeptidase (EC 2.3.2.1; gamma-GT) activity. GSH levels were measured simultaneously in various organs after oral GSH administration to untreated rats and rats treated with L-buthionine sulfoximine (BSO) or acivicin (AT125). BSO selectively inhibits GSH intracellular synthesis and AT125 is a… CONTINUE READING