Effect of orally administered epidermal growth factor on intestinal recovery of neonatal pigs infected with rotavirus.

@article{Zijlstra1994EffectOO,
  title={Effect of orally administered epidermal growth factor on intestinal recovery of neonatal pigs infected with rotavirus.},
  author={Ruurd T. Zijlstra and Jack Odle and William F. Hall and Bryon W Petschow and Howard B. Gelberg and Richard E. Litov},
  journal={Journal of pediatric gastroenterology and nutrition},
  year={1994},
  volume={19 4},
  pages={382-90}
}
The effect of oral epidermal growth factor (EGF) on histological and biochemical changes in epithelium in the small intestine was studied in colostrum-deprived neonatal pigs. Forty-eight pigs were infected at 4 days of age with 2 x 10(7) plaque-forming units of porcine group A rotavirus and orally fed a simulated sow-milk diet supplemented with 0.0, 0.5, or 1.0 mg/L recombinant human EGF. Sixteen noninfected pigs were fed a diet without EGF supplementation. Infected pigs developed severe… CONTINUE READING