Effect of oral creatine supplementation on urinary methylamine, formaldehyde, and formate.

@article{Poortmans2005EffectOO,
  title={Effect of oral creatine supplementation on urinary methylamine, formaldehyde, and formate.},
  author={Jacques Remi Poortmans and Alain Kumps and Pierre Duez and Aline Fofonka and Alain Carpentier and Marc Francaux},
  journal={Medicine and science in sports and exercise},
  year={2005},
  volume={37 10},
  pages={
          1717-20
        }
}
PURPOSE It has been claimed that oral creatine supplementation might have potential cytotoxic effects on healthy consumers by increasing the production of methylamine and formaldehyde. Despite this allegation, there has been no scientific evidence obtained in humans to sustain or disprove such a detrimental effect of this widely used ergogenic substance. METHODS Twenty young healthy men ingested 21 g of creatine monohydrate daily for 14 consecutive days. Venous blood samples and 24-h urine… CONTINUE READING

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