Effect of oral cholecalciferol supplementation at physiological and supraphysiological doses in naturally vitamin D3-deficient subterranean damara mole rats (Cryptomys damarensis).

@article{Buffenstein1991EffectOO,
  title={Effect of oral cholecalciferol supplementation at physiological and supraphysiological doses in naturally vitamin D3-deficient subterranean damara mole rats (Cryptomys damarensis).},
  author={R. Buffenstein and D. C. Skinner and S. Yahav and G. Moodley and M. Cavaleros and D. Zachen and F. Ross and J. Pettifor},
  journal={The Journal of endocrinology},
  year={1991},
  volume={131 2},
  pages={
          197-202
        }
}
The damara mole rat, Cryptomys damarensis, is a strictly subterranean dwelling herbivorous rodent that in its natural habitat has no access to any obvious source of cholecalciferol (D3). We examined the effects of D3 supplementation, at physiological and supraphysiological doses, on calcium metabolism, plasma concentrations of calcium and alkaline phosphatase (ALP) and D3 metabolites. Animals not receiving a D3 supplement maintained normal plasma calcium concentrations. In addition, they… Expand
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