Effect of oral administration of Lactobacillus plantarum HY7714 on epidermal hydration in ultraviolet B-irradiated hairless mice.

  title={Effect of oral administration of Lactobacillus plantarum HY7714 on epidermal hydration in ultraviolet B-irradiated hairless mice.},
  author={J-H Ra and Dong Eun Lee and Sung Hwan Kim and Ji-Woong Jeong and Hyung-Keun Ku and Tae-Youl Kim and Il-dong Choi and Woonhee Jeung and Jaehun Sim and Y. T. Ahn},
  journal={Journal of microbiology and biotechnology},
  volume={24 12},
In this study, we evaluated the effect of Lactobacillus plantarum HY7714 on skin hydration in human dermal fibroblasts and in hairless mice. In Hs68 cells, L. plantarum HY7714 not only increased the serine palmitoyltransferase (SPT) mRNA level, but also decreased the ceramidase mRNA level. In order to confirm the hydrating effects of L. plantarum HY7714 in vivo, we orally administered vehicle or L. plantarum HY7714 at a dose of 1 × 10(9) CFU/day to hairless mice for 8 weeks. In hairless mice, L… 

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