Effect of ondansetron on nausea and vomiting after middle ear surgery during general anaesthesia.

@article{Honkavaara1996EffectOO,
  title={Effect of ondansetron on nausea and vomiting after middle ear surgery during general anaesthesia.},
  author={Pekka Honkavaara},
  journal={British journal of anaesthesia},
  year={1996},
  volume={76 2},
  pages={316-8}
}
The efficacy of ondansetron 4 mg and 8 mg was compared with placebo in the reduction of postoperative nausea, retching and vomiting (PONV) after middle ear surgery during general anaesthesia, in 75 patients, in a double-blind and randomized study. Both doses of ondansetron were predictors for a decrease in PONV and the number of doses of rescue antiemetic needed per patient (droperidol: from 0.72 in the placebo group to 0.32 in both the 4-mg and 8-mg groups). No reduction in PONV was observed… CONTINUE READING

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