Effect of omeprazole on concentrations of clarithromycin in plasma and gastric tissue at steady state.

@article{Gustavson1995EffectOO,
  title={Effect of omeprazole on concentrations of clarithromycin in plasma and gastric tissue at steady state.},
  author={Linda E. Gustavson and Jackie Kaiser and Allan L. Edmonds and Charles S. Locke and M. Debartolo and Dennis W. Schneck},
  journal={Antimicrobial agents and chemotherapy},
  year={1995},
  volume={39 9},
  pages={
          2078-83
        }
}
This study was conducted to determine (i) the effect of omeprazole on steady-state concentrations of clarithromycin and 14-(R)-hydroxyclarithromycin in plasma and gastric mucosa, (ii) the effect of clarithromycin on steady-state concentrations of omeprazole in plasma, and (iii) the effect of clarithromycin on the suppression of gastric acid secretion by omeprazole. Twenty healthy, Helicobacter pylori-negative male subjects completed this three-period, double-blind, randomized crossover study… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 39 CITATIONS

Kill kinetics of antimicrobial agents against Helicobacter pylori.

  • The Journal of antimicrobial chemotherapy
  • 1996
VIEW 3 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

Similar Papers

Loading similar papers…