Effect of oligofructose-enriched inulin (OF-IN) on bacterial composition and disease activity of patients with Crohn's disease: results from a double-blinded randomised controlled trial.

@article{Joossens2012EffectOO,
  title={Effect of oligofructose-enriched inulin (OF-IN) on bacterial composition and disease activity of patients with Crohn's disease: results from a double-blinded randomised controlled trial.},
  author={Marie Joossens and Vicky De Preter and Vera Ballet and Kristin Verbeke and P. R. Rutgeerts and S{\'e}verine Vermeire},
  journal={Gut},
  year={2012},
  volume={61 6},
  pages={958}
}
With great interest, we have read the manuscript by Benjamin et al on the effect of fructo-oligosaccharides in patients with active Crohn’s disease (CD). We recently completed a single-centre randomised placebo-controlled trial with a similar study design. In our study, 67 patients with inactive and mild to moderately active CD were randomised to receive oligofructose-enriched inulin (OF-IN) or placebo 10 g twice daily for 4 weeks. Clinical disease activity was assessed according to the Harvey… CONTINUE READING
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