Effect of obestatin on insulin, glucagon and somatostatin secretion in the perfused rat pancreas.

Abstract

Obestatin is a 23-amino acid peptide derived from preproghrelin, purified from stomach extracts and detected in peripheral plasma. In contrast to ghrelin, obestatin has been reported to inhibit appetite and gastric motility. However, these effects have not been confirmed by some groups. Obestatin was originally proposed to be the ligand for GPR39, a… (More)
DOI: 10.1016/j.regpep.2008.08.003

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