Effect of normal endometrial stroma on growth and differentiation in Ishikawa endometrial adenocarcinoma cells.

@article{Arnold2002EffectON,
  title={Effect of normal endometrial stroma on growth and differentiation in Ishikawa endometrial adenocarcinoma cells.},
  author={Julia T. Arnold and Bruce A. Lessey and Markku Sepp{\"a}l{\"a} and David G. Kaufman},
  journal={Cancer research},
  year={2002},
  volume={62 1},
  pages={
          79-88
        }
}
Endometrial cancer is characterized by alterations in the stromal cells and the supporting extracellular matrix in addition to the intrinsic alterations of the malignant epithelial cells. We have developed a cell culture model that demonstrates the role of stromal cells in the regulation of proliferation, hormone responsiveness, and differentiation of an endometrial adenocarcinoma cell line (Ishikawa). Conditioned medium (CM) was collected from normal primary human endometrial stromal cells… CONTINUE READING
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