Effect of nitric oxide synthase inhibition on postischemic cerebral hyperemia.

@article{Greenberg1995EffectON,
  title={Effect of nitric oxide synthase inhibition on postischemic cerebral hyperemia.},
  author={Robert Steven Greenberg and Mark A. Helfaer and Jeffrey R. Kirsch and Richard J. Traystman},
  journal={The American journal of physiology},
  year={1995},
  volume={269 1 Pt 2},
  pages={H341-7}
}
We tested the hypothesis that inhibition of nitric oxide synthase (NOS) activity in brain before ischemia decreases postischemic hyperemia. Pentobarbital-anesthetized piglets underwent 15 min of complete global cerebral ischemia induced by elevation of intracranial pressure followed by 20 min of reperfusion. Before ischemia the animals were randomly… CONTINUE READING