Effect of nitric oxide on renin secretion. I. Studies in isolated juxtaglomerular granular cells.

@article{Greenberg1995EffectON,
  title={Effect of nitric oxide on renin secretion. I. Studies in isolated juxtaglomerular granular cells.},
  author={Suzanne G Greenberg and Xiao-gu He and J{\"u}rgen B. Schnermann and Josephine P. Briggs},
  journal={The American journal of physiology},
  year={1995},
  volume={268 5 Pt 2},
  pages={F948-52}
}
Experiments were performed on juxtaglomerular granular cells (JGC) in short-term primary culture to determine the direct immediate effect of NO on renin secretion and to test whether JGC are able to generate NO. Renin secretion was measured repeatedly over short time intervals in a cell superfusion system. Renin release did not significantly decrease over a 40-min observation period in untreated JGC. Addition of sodium nitroprusside (SNP) caused a reduction in renin release (measured in nano… CONTINUE READING
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