Effect of nimodipine on male reproductive functions in rats.

@article{Saha2000EffectON,
  title={Effect of nimodipine on male reproductive functions in rats.},
  author={Lekha Saha and Vijay. K. Bhargava and S. K. Garg and Siddhartha Majumdar},
  journal={Indian journal of physiology and pharmacology},
  year={2000},
  volume={44 4},
  pages={449-55}
}
Nimodipine, a dihydropyridine calcium channel blocker, was administered orally using two different doses (40 mg and 60 mg/kg/day) to rats. Both short term (2 weeks) and long term (6 weeks) effects of the drug were observed. The drug administration resulted in a marked decrease in sperm density, sperm motility and acrozomal reaction. Zona-pellucida… CONTINUE READING