Effect of nimodipine on intracellular brain pH, cortical blood flow, and EEG in experimental focal cerebral ischemia.

@article{Meyer1986EffectON,
  title={Effect of nimodipine on intracellular brain pH, cortical blood flow, and EEG in experimental focal cerebral ischemia.},
  author={Fredric Bruce Meyer and Robert E. Anderson and Tony L. Yaksh and Thoralf M. Sundt},
  journal={Journal of neurosurgery},
  year={1986},
  volume={64 4},
  pages={
          617-26
        }
}
Intracellular brain pH, cortical blood flow, and electroencephalograms (EEG's) were recorded in severely and moderately ischemic regions in 10 control and 10 nimodipine-treated rabbits prior to and following major branch occlusion of the middle cerebral artery (MCA). Preocclusion cortical blood flow was 51 ml/100 gm/min and intracellular brain pH was 7.01 in both the control and the treated animals. After MCA occlusion, the severely ischemic regions in the control group showed initial and 4… CONTINUE READING
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