Effect of nilvadipine on high-voltage activated Ca2+ channels in rat CNS neurons.

@article{Ishibashi1997EffectON,
  title={Effect of nilvadipine on high-voltage activated Ca2+ channels in rat CNS neurons.},
  author={Hitoshi Ishibashi and Jeong Seop Rhee and Norio Akaike},
  journal={Neuroreport},
  year={1997},
  volume={8 4},
  pages={853-7}
}
The effect of nilvadipine, a dihydropyridine derivative, on high-voltage activated (HVA) Ca2+ channels was investigated in freshly dissociated rat frontal cortical neurons. The cortical neurons were observed to have five pharmacologically distinct HVA Ca2+ channel subtypes consisting of the L-, N-, P-, O- and R-types. Nilvadipine selectively inhibited the L… CONTINUE READING