Effect of neurokinins on canine prostate cell physiology

@article{Walden2005EffectON,
  title={Effect of neurokinins on canine prostate cell physiology},
  author={Paul D. Walden and Dorene Marinese and Dinesh Kumar Srinivasan and Elda Tzoumaka and Harley T. Syyong and Anthony P.D.W. Ford and Anindya Bhattacharya},
  journal={The Prostate},
  year={2005},
  volume={63}
}
Sensory peptide neurotransmitters have been implicated as significant regulators of prostate growth. This study was designed to evaluate the role of neurokinins in proliferation, differentiation, and contraction of canine prostate cells in culture. 
Effect of Onabotulinum Toxin A on Substance P and Receptor Neurokinin 1 in the Rat Ventral Prostate.
TLDR
BoNTA treatment decreases substance P in the rat VP and its receptor neurokinin 1 localization and quantification were performed by counting the number of stained neurons and nerve bundles, by semi-quantitative immunohistochemical analysis and by western analysis.
Neuropeptide Profiles of Mammalian Male Genital Tract: Distribution and Functional Relevance in Reproduction
TLDR
It was revealed from documented reports that the vast majority of neuropeptides present in the autonomic nerve supply to the male genital tract probably coexist with other peptides or with various neurotransmitters (tyrosine hydroxylase, dopamine beta hydroxyase, and 5-hydroxytryptamine).
Age-related changes in the innervation of the prostate gland
TLDR
The influence of the sympathetic nervous system on benign prostatic hyperplasia is well documented and the possibility of a link between changes in autonomic innervation and prostate cancer progression is considered.

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