Effect of natural ageing and antioxidant inhibition on liver antioxidant enzymes, glutathione system, peroxidation, and oxygen consumption inRana perezi

@article{LpezTorres1991EffectON,
  title={Effect of natural ageing and antioxidant inhibition on liver antioxidant enzymes, glutathione system, peroxidation, and oxygen consumption inRana perezi},
  author={M{\'o}nica L{\'o}pez-Torres and R. P{\'e}rez-Campo and G. Barja de Quiroga},
  journal={Journal of Comparative Physiology B},
  year={1991},
  volume={160},
  pages={655-661}
}
A study of the physiological role of oxygen free radicals in relation to the ageing process was performed using the liver ofRana perezi, an animal with a moderate rate of oxygen consumption and a life span substantially longer than that of laboratory rodents. Among the five different antioxidant enzymes only superoxide dismutase (SOD) showed an age-dependent decrease. Cytochrome oxidase (COX), glutathione status, in vivo and in vitro liver peroxidation, and metabolic rate did not vary as a… CONTINUE READING
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