OBJECTIVE To discuss the effect of nasal endoscopy-assisted adenoidectomy with debrided on the development of pediatric chronic sinusitis and otitis media with effusion. METHOD Fifteen cases of hypertrophied adenoid with pediatric chronic sinusitis and/or otitis media with effusion were treated with nasal endoscopy-assisted adenoidectomy and medicines followed. RESULT No remainder of adenoid was left, no complication occurred and snoring disappeared in all patients. Pediatric chronic sinusitis and/or otitis media with effusion recovered with medicines after adenoidectomy. CONCLUSION Nasal endoscopy-assisted adenoidectomy with debrided was an minimally invasive and effective treatment for hypertrophied adenoid, as well as contributed to the development of pediatric chronic sinusitis and otitis media with effusion.