Effect of narcotic premedication on scintigraphic evaluation of gallbladder perforation.

@article{Sefczek1985EffectON,
  title={Effect of narcotic premedication on scintigraphic evaluation of gallbladder perforation.},
  author={D M Sefczek and Purna Sharma and George Isaacs and George J. Brodmerkel and M H Adatepe and O M Powell and Kenneth Nichols},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1985},
  volume={26 1},
  pages={51-3}
}
A case of gallbladder perforation is presented in which a small bile leak was demonstrated by cholescintigraphy while the patient was receiving meperidine, but not after meperidine was discontinued. The scintigrams obtained during meperidine therapy also showed a pattern of bile-duct obstruction. It is suggested that increased biliary pressure secondary to meperidine administration permitted visualization of the leak. Use of narcotic drugs may be a useful pharmacologic intervention in cases of… CONTINUE READING