Effect of nadolol, a beta-adrenoceptor blocking agent, on myocardial metabolism in the dog ischaemic heart.

Abstract

The effect of nadolol at a dose of 1 mg kg-1, i.v. on the ischaemic myocardial metabolism has been examined in the dog. Ischaemia was induced by ligating the left anterior descending coronary artery for 3 min, and nadolol was injected 5 min before ligation. Ischaemia caused myocardial metabolic changes; it decreased energy charge potential and inhibited… (More)

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Cite this paper

@article{Ichihara1987EffectON, title={Effect of nadolol, a beta-adrenoceptor blocking agent, on myocardial metabolism in the dog ischaemic heart.}, author={Kazuo Ichihara and Yoshimitsu Abiko}, journal={The Journal of pharmacy and pharmacology}, year={1987}, volume={39 8}, pages={604-8} }