Effect of myo-inositol on the glycerophospholipid composition of adult and fetal rat lung tissue.

@article{Quirk1984EffectOM,
  title={Effect of myo-inositol on the glycerophospholipid composition of adult and fetal rat lung tissue.},
  author={J. Gerald Quirk and Bernd Baumgarten and John E. Bleasdale},
  journal={Journal of perinatal medicine},
  year={1984},
  volume={12 4},
  pages={201-10}
}
In many species including man, the second most abundant lipid in lung surfactant is phosphatidylglycerol (PG) which may comprise 10% of the total lipid in surfactant from mature lungs. Infants delivered before their surfactant contained a large amount of PG are at greater risk of succumbing to hyaline membrane disease. Regulation of the PG content of lung surfactant is not understood completely, but the reciprocal changes in the amount of phosphatidylinositol (PI) and PG in surfactant as the… CONTINUE READING