Effect of mycophenolate mofetil monotherapy on T-cell functions and inosine monophosphate dehydrogenase activity in patients undergoing a kidney transplantation.

@article{Kamar2006EffectOM,
  title={Effect of mycophenolate mofetil monotherapy on T-cell functions and inosine monophosphate dehydrogenase activity in patients undergoing a kidney transplantation.},
  author={Nassim Kamar and Hans-H. Neumayer and Jochen Nolting and T. Jeffery Holland Boehler and Pia Hambach and Lutz Liefeldt and Jochen Klupp and Klemens Budde},
  journal={Transplantation proceedings},
  year={2006},
  volume={38 7},
  pages={
          2292-4
        }
}
The aim of this study was to assess the effects of 1 g of mycophenolate mofetil (MMF) on T-cell function and inosine monophosphate dehydrogenase (IMPDH) activity among patients undergoing kidney transplantation. Five patients undergoing renal transplantation from a living donor were enrolled in this study. Compared to baseline (before MMF intake), CD25 and CD71 expression were significantly decreased during the first hour following MMF intake. T-cell proliferation and IMPDH activity also… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

Pharmacodynamic evaluation of the first dose of mycophenolate mofetil before kidney transplantation.

  • Clinical journal of the American Society of Nephrology : CJASN
  • 2009
VIEW 1 EXCERPT
CITES BACKGROUND

Lymphocyte activation and correlation with IMPDH activity under therapy with mycophenolate mofetil.

  • Clinica chimica acta; international journal of clinical chemistry
  • 2008
VIEW 1 EXCERPT
CITES BACKGROUND