Effect of multiple, simultaneous vaccines on polio seroresponse and associated health outcomes.

  title={Effect of multiple, simultaneous vaccines on polio seroresponse and associated health outcomes.},
  author={Michael P. Broderick and M. Steven Oberste and Deborah Moore and Sandra Romero-Steiner and Christian J. Hansen and Dennis J. Faix},
  volume={33 24},

Tables from this paper

Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine and Commonly Administered Vaccines After Coadministration
With no clinically relevant vaccine interactions or impact on vaccine reactogenicity or safety, these results support the coadministration of MenACWY-CRM with routine vaccines in all age groups.
Immune Responses in U.S. Military Personnel Who Received Meningococcal Conjugate Vaccine (MenACWY) Concomitantly with Other Vaccines Were Higher than in Personnel Who Received MenACWY Alone
Additional prospective randomized clinical trials are needed to confirm the observed differences among groups in the immune response to MenACWY when given concomitantly with other vaccines to U.S. military personnel.
Immunogenicity of Viral Vaccines in the Italian Military
An excellent vaccine immunogenicity, a calculated long antibody persistence, and apparent lack of vaccine interference were observed.
Where We Stand In the Global Eradication of Polio
Eradicable infectious agents are those where the chain of transmission can be broken by an intervention and where there is no reservoir such as a chronic or persistent carrier state, chronic
A Brief History of Anti-vaccination Movements
The story of the anti-vaccination movements, which have opposed vaccinations for health, religious and political reasons, is a story that is as old as the very practice of inoculating smallpox
Vaccines: Are they Worth a Shot?


Factors affecting the immunogenicity of oral poliovirus vaccine: a prospective evaluation in Brazil and the Gambia. World Health Organization Collaborative Study Group on Oral Poliovirus Vaccine.
  • Medicine
    The Journal of infectious diseases
  • 1995
OPV containing twice the standard potency of Sabin type 1 virus increased seroconversion rates to P1 by 8% in Brazil and 15% in the Gambia and P < .001 in both countries.
Diminution of the anti-polyribosylribitol phosphate response to a combined diphtheria-tetanus-acellular pertussis/Haemophilus influenzae type b vaccine by concurrent inactivated poliovirus vaccination
In this trial concurrent IPV appeared to interfere with the anti-PRP response to DTaP/Hib vaccine, suggesting that introduction of new vaccines may require evaluation of immune responses to all concurrently administered vaccines.
Safety and immunogenicity of Haemophilus influenzae vaccine (tetanus toxoid conjugate) administered concurrently or combined with diphtheria and tetanus toxoids, pertussis vaccine and inactivated poliomyelitis vaccine to healthy infants at two, four and six months of age.
Interactions observed among the components of the pentavalent vaccine may be of concern because they might influence antibody persistence until the fourth dose is administered.
Evaluation of a diphtheria–tetanus–acellular pertussis–inactivated poliovirus–Haemophilus influenzae type b vaccine given concurrently with meningococcal group C conjugate vaccine at 2, 3 and 4 months of age
Coadministration of MCC vaccine can influence the Hib response, and the MCC response to a tetanus conjugate can be influenced by the nature of the coadministered DTP-Hib vaccine.
Immunization of Teenagers with a Fifth Dose of Reduced DTaP-IPV Induces High Levels of Pertussis Antibodies with a Significant Increase in Opsonophagocytic Activity
Waning vaccine-induced immunity against Bordetella pertussis is observed among adolescents and adults and correlation analyses between the different assays suggest that antibodies against FHA and PRN contribute the most to the OPA and IgG binding.
Reduced Response to Multiple Vaccines Sharing Common Protein Epitopes That Are Administered Simultaneously to Infants
Infants simultaneously receiving a tetravalent pneumococcal vaccine conjugated to TT (PncT) and a diphtheria-tetanus-pertussis–poliovirus–Haemophilus influenzae type b-Tetanus conjugate vaccine showed significantly lower anti-H.
This study showed that the incidence and manifestations of allergy during the first 2 1 ⁄2 years of life was not increased after pertussis vaccination, and previous studies using smaller numbers of children have suggested an association.
Pertussis vaccination and asthma: is there a link?
It appears that where the overall population of infants is concerned, the use of acellular pertussis vaccine might be one of the main changes to be expected in the near future, and unexpected findings apparently linked with the current inactivated bacterial vaccine are reported.