Effect of monosodium glutamate on apoptosis and Bcl-2/Bax protein level in rat thymocyte culture.

@article{Pavlovic2007EffectOM,
  title={Effect of monosodium glutamate on apoptosis and Bcl-2/Bax protein level in rat thymocyte culture.},
  author={Vlastimir D. Pavlovic and Sne{\vz}ana Ceki{\'c} and Gordana Koci{\'c} and Dragana Sokolovi{\'c} and Vladimir A. Zivkovic},
  journal={Physiological research},
  year={2007},
  volume={56 5},
  pages={619-26}
}
Monosodium glutamate (MSG), the sodium salt of glutamate, is commonly used as a flavor enhancer in modern nutrition. Recent studies have shown the existence of glutamate receptors on lymphocytes, thymocytes and thymic stromal cells. In this study, we evaluated the in vitro effect of different MSG concentrations on rat thymocyte apoptosis and expression of two apoptosis-related proteins, Bcl-2 and Bax. Rat thymocytes, obtained from male Wistar rats, were exposed to increasing concentrations of… CONTINUE READING

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