Effect of microgravity and hypergravity on deposition of 0.5- to 3-micron-diameter aerosol in the human lung.

@article{Darquenne1997EffectOM,
  title={Effect of microgravity and hypergravity on deposition of 0.5- to 3-micron-diameter aerosol in the human lung.},
  author={Chantal Darquenne and Manuel Paiva and John B. West and G. Kim Prisk},
  journal={Journal of applied physiology},
  year={1997},
  volume={83 6},
  pages={2029-36}
}
We measured intrapulmonary deposition of 0. 5-, 1-, 2-, and 3-micron-diameter particles in four subjects on the ground (1 G) and during parabolic flights both in microgravity (microG) and at approximately 1.6 G. Subjects breathed aerosols at a constant flow rate (0.4 l/s) and tidal volume (0.75 liter). At 1 G and approximately 1.6 G, deposition increased with increasing particle size. In microG, differences in deposition as a function of particle size were almost abolished. Deposition was a… CONTINUE READING

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