Effect of mexiletine on lipid peroxidation and early ultrastructural findings in experimental spinal cord injury.

@article{Kaptanolu1999EffectOM,
  title={Effect of mexiletine on lipid peroxidation and early ultrastructural findings in experimental spinal cord injury.},
  author={Erkan Kaptanoğlu and H. H. Caner and H. Selçuk S{\"u}r{\"u}c{\"u} and Filiz Akbiyik},
  journal={Journal of neurosurgery},
  year={1999},
  volume={91 2 Suppl},
  pages={200-4}
}
OBJECT The purpose of this study was to investigate the effect of mexiletine on lipid peroxidation and on ultrastructural findings after induced spinal cord injury (SCI). The authors also compared the activity of mexiletine to that of the well-known antioxidant, methylprednisolone sodium succinate (MPSS). METHODS Wistar rats were divided into seven groups, (Groups 1-7). Those in Groups 1 and 2 were control animals that underwent laminectomy only, after which nontraumatized spinal cord samples… CONTINUE READING
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