Corpus ID: 25286534

Effect of metronidazole on platelet aggregation.

@article{PradoFranceschi1989EffectOM,
  title={Effect of metronidazole on platelet aggregation.},
  author={J. Prado-Franceschi and E. Antunes},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={1989},
  volume={22 12},
  pages={
          1497-500
        }
}
  • J. Prado-Franceschi, E. Antunes
  • Published 1989
  • Chemistry, Medicine
  • Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
  • The effects of metronidazole on platelet aggregation induced by several agonists were studied on guinea pig and human platelet-rich plasma. Metronidazole (0.25-2.5 mg/ml) showed a dose-dependent inhibitory effect on in vitro aggregation of platelets from either source induced by adenosine-5-diphosphate (ADP), platelet aggregating factor (PAF), epinephrine, collagen or convulxin (extracted from Crotalus durissus terrificus venom). Total or partial inhibition was also detected in metronidazole… CONTINUE READING
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