Effect of metrazol on the discharge characteristics of muscle spindle afferents from the hind limb of the rat.


The nature of altered fusimotor discharge induced by subconvulsive doses of Metrazol has been investigated in deeply anaesthetized rats. Large amplitude stretching (ramp and hold or sinusoidal) of the appropriate muscle during the course of drug action shows Metrazol to have a predominant gamma d effect on primaries, and an exclusive gamma s effect on… (More)


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