Effect of methyl methacrylate on isolated atria and interaction with isoproterenol, atropine and calcium chloride.

@article{Baran1992EffectOM,
  title={Effect of methyl methacrylate on isolated atria and interaction with isoproterenol, atropine and calcium chloride.},
  author={K P Baran and William M. Davis and Irene Waters},
  journal={General pharmacology},
  year={1992},
  volume={23 4},
  pages={781-5}
}
1. Spontaneous rate and contractile force of isolated rat and rabbit atria suspended in a tissue bath were recorded before and after drugs. Methyl methacrylate monomer (MMA) alone both decreased force and increased rate dose-dependently. 2. Concentrations of calcium chloride or isoproterenol that alone increased both rate and force of rat atrial contraction were fully and only partially able, respectively, to restore force to normal after MMA. 3. Atropine prevented changes in rat atrial… CONTINUE READING

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