Effect of methoxyethanol, cyclophosphamide and cadmium on metallothionein levels during prenatal development in the mouse.

Abstract

Three known teratogenic agents--methoxyethanol (ME), cyclophosphamide (CP) and cadmium (Cd)--are possible inducers of metallothionein (MT) in the embryo and/or in the fetus. Their effect on the MT levels of forelimbs, brain and liver during prenatal development and in dam's liver was studied in the mouse to elucidate whether MT could be used as an early… (More)

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