Effect of metformin on bone marrow progenitor cell differentiation: in vivo and in vitro studies.

@article{Molinuevo2010EffectOM,
  title={Effect of metformin on bone marrow progenitor cell differentiation: in vivo and in vitro studies.},
  author={Mar{\'i}a Silvina Molinuevo and Le{\'o}n Schurman and Antonio Desmond McCarthy and Ana Mar{\'i}a Cortizo and Mar{\'i}a Jos{\'e} Tolosa and Mar{\'i}a Virginia Gangoiti and Ver{\'o}nica Arnol and Claudia Sedlinsky},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2010},
  volume={25 2},
  pages={211-21}
}
Diabetes mellitus is associated with bone loss. Patients with type 2 diabetes are frequently treated with oral antidiabetic drugs such as sulfonylureas, biguanides, and thiazolidinediones. Rosiglitazone treatment has been shown to increase adipogenesis in bone marrow and to induce bone loss. In this study we evaluated the effect of in vivo and in vitro… CONTINUE READING