Alutin, et al., in: Bacterial Toxins [in Russian
- O. I. Sal'nikova, I.M.K.K. Rozhkov
The use of immunomodulators (IM) is being increasingly extended to the treatment of various pathological states. Reports have appeared about their capacity .to influence the susceptibility of the organism to var io~ toxic stimuli. The goal of this work was a study of the influence of IM of metalloorganic nature Oil the susceptibility of mice of different strains to "mouse toxin" (MT) of plague microbes. MT is a plague microbederived lethal protein toxin of high activity. Keeping in mind the diurnal variations in the organism's resistance to the toxic effect of various compounds, the experiments were carried out at different times of the day.