Effect of metal ions on the stability of metallothionein in the degradation by cellular fractions in vitro

@article{Hahn2001EffectOM,
  title={Effect of metal ions on the stability of metallothionein in the degradation by cellular fractions in vitro},
  author={Si Houn Hahn and Ook Joon Yoo and William A Gahl},
  journal={Experimental & Molecular Medicine},
  year={2001},
  volume={33},
  pages={32-36}
}
Metallothioneins (MT), small molecular weight metal binding proteins are known to play an important protective role against heavy metal toxicity, either as antioxidants or pre-oxidants. However, the mode of metabolic fate of MTs in various metal complexes is not clearly understood. This study was carried out to better understand the mode of selective turnover rate of various form of MT in complexes with different metals. The degradation of in vitro translated mouse 35S-cysteine-MT was examined… CONTINUE READING