Effect of memantine treatment on regional cortical metabolism in Alzheimer's disease.

Abstract

OBJECTIVES Cortical systems involved in the response to medication treatment for Alzheimer's disease (AD) are poorly understood. Preclinical studies have demonstrated the effect of memantine on neuroreceptors and cell physiology, although the impact of treatment on cortical activity in vivo is not known. DESIGN F-fluorodeoxyglucose positron emission… (More)
DOI: 10.1097/JGP.0b013e3181ca3a4e

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