Effect of memantine on neuroretinal function and retinal vascular changes of streptozotocin-induced diabetic rats.

@article{Kusari2007EffectOM,
  title={Effect of memantine on neuroretinal function and retinal vascular changes of streptozotocin-induced diabetic rats.},
  author={Jyotirmoy X. Kusari and Sheila X. Zhou and Edwin U. Padillo and Kenneth G Clarke and Daniel W. Gil},
  journal={Investigative ophthalmology & visual science},
  year={2007},
  volume={48 11},
  pages={
          5152-9
        }
}
PURPOSE To test whether chronic memantine (MEM) treatment improves retinal function and prevents neurodegeneration and vascular changes in the retinas of streptozotocin (STZ)-induced diabetic rats. METHODS Based on basal body weight and blood glucose, Brown Norway (BN) rats were divided into three groups. One group of rats was treated with vehicle (VEH), and the other two groups were treated with 65 mg/kg STZ. After 7 days, VEH-treated rats were treated further with a second VEH, and STZ… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 57 CITATIONS

Increased D-serine in the aqueous and vitreous humour in patients with proliferative diabetic retinopathy.

  • Clinical & experimental ophthalmology
  • 2014
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2008
2019

CITATION STATISTICS

  • 5 Highly Influenced Citations

  • Averaged 6 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 69 REFERENCES

VEGF-initiated blood-retinal barrier breakdown in early diabetes.

  • Investigative ophthalmology & visual science
  • 2001
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

A new view of diabetic retinopathy: a neurodegenerative disease of the eye

AJ Barber
  • Prog Neuro-Psychopharmacol Biol Psychiatry
  • 2003
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Diabetic Retinopathy and the NMDA Receptor.

  • Drug news & perspectives
  • 2002
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Insulin protection against carbonyl and hyperglycemic stress - induced neuronal cell apopto

M Okouchi, N Okayama, R Kimura
  • Diabetes .
  • 2007

Insulin protection against carbonyl and hyperglycemic stress-induced neuronal cell apoptosis

M Okouchi, N Okayama, R Kimura
  • Diabetes. 2007;56(suppl 1):A345
  • 2007
VIEW 1 EXCERPT

Similar Papers

Loading similar papers…