Effect of medium type, age and aeration on the MICs of tigecycline and classical tetracyclines.

@article{Hope2005EffectOM,
  title={Effect of medium type, age and aeration on the MICs of tigecycline and classical tetracyclines.},
  author={R. P. Hope and Marina Warner and Shazad Mushtaq and Michael E. Ward and Tina Parsons and David Martin Livermore},
  journal={The Journal of antimicrobial chemotherapy},
  year={2005},
  volume={56 6},
  pages={1042-6}
}
BACKGROUND Tigecycline is a minocycline derivative, belonging to a chemical class prone to oxidation and to medium-related effects on susceptibility. We therefore studied the effect of medium type and age on the tigecycline MICs found in broth and on agar by the Clinical Laboratory Standards Institute and British Society for Applied Chemotherapy methods. METHODS MICs of tigecycline, minocycline and tetracycline were determined for 96 non-fastidious bacteria and 20 streptococci using Mueller… CONTINUE READING