Effect of medium composition on the production of tetanus toxin by Clostridium tetani.

Abstract

The tetanus toxin is a neurotoxin synthesized by the bacillus Clostridium tetani that, after detoxification with formaldehyde, still exhibits antigenic and immunologic properties, hence its denomination of tetanus toxoid. Such a neurotoxin is produced by cultivation of the microorganism in vegetative form on a relatively complex specific medium containing… (More)

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Cite this paper

@article{Fratelli2005EffectOM, title={Effect of medium composition on the production of tetanus toxin by Clostridium tetani.}, author={Fernando Fratelli and Tatiana Joly Siquini and Sally M{\"u}ller Affonso Prado and Hisako Gondo Higashi and Attilio Converti and Jo{\~a}o Carlos Monteiro de Carvalho}, journal={Biotechnology progress}, year={2005}, volume={21 3}, pages={756-61} }