Effect of maternal tobacco smoke exposure on the placental transcriptome.

  title={Effect of maternal tobacco smoke exposure on the placental transcriptome.},
  author={Hana Bruchova and Al{\vz}běta Va{\vs}{\'i}kov{\'a} and Michaela Dostalova Merkerova and Alena Milcov{\'a} and J. Rick Topinka and Ivan Bala{\vs}{\vc}{\'a}k and Anna Pastorkov{\'a} and Radim J. {\vS}r{\'a}m and Radim Brdi{\vc}ka},
  volume={31 3},
Smoking in pregnancy increases a woman's risk of preterm delivery resulting in serious neonatal health problems and chronic lifelong disabilities for the children (e.g., mental retardation, learning problems). To study the effects of tobacco smoke on the placental transcriptome, we performed gene expression profiling on placentas from women exposed to tobacco smoke in pregnancy (N = 12) and from those without significant exposure (N = 64). Gene expression profiles were determined by Illumina… CONTINUE READING