Effect of maternal restraint stress during gestation on temporal lipopolysaccharide-induced neuroendocrine and immune responses of progeny.

@article{Collier2011EffectOM,
  title={Effect of maternal restraint stress during gestation on temporal lipopolysaccharide-induced neuroendocrine and immune responses of progeny.},
  author={Claiborne Collier and Phillip N Williams and Jeffery A. Carroll and Thomas H. Welsh and Jamie C Laurenz},
  journal={Domestic animal endocrinology},
  year={2011},
  volume={40 1},
  pages={40-50}
}
The impact of gestational dam restraint stress on progeny immune and neuroendocrine temporal hormone responses to lipopolysaccharide (LPS) challenge was assessed. Maternal stress (5-min snout snare restraint stress during days 84 to 112 of gestation) increased (P < 0.05) the magnitude of tumor necrosis factor (TNF)-α, interleukin-6, epinephrine (E), norepinephrine, and serum amyloid A (SAA) production following LPS infusion in the offspring. Moreover, these effects appear to be dependent on… CONTINUE READING
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