Effect of maternal isoxsuprine on fetal rabbit lung biochemical maturation.

@article{Hayden1977EffectOM,
  title={Effect of maternal isoxsuprine on fetal rabbit lung biochemical maturation.},
  author={William T. Hayden and E. Burt Olson and Richard D. Zachman},
  journal={American journal of obstetrics and gynecology},
  year={1977},
  volume={129 6},
  pages={
          691-4
        }
}
Isoxsuprine was given intramuscularly for 24 hours to pregnant rabbits at 26 to 27 days' gestation. There was no effect on fetal weight within one day of the last injection. Fetuses of isoxsuprine-treated mothers had higher lung lecithin (6.67 micron per gram +/- 2.81) and higher tracheal wash lecithin/sphingomyelin (L/S) ratios (5.85 +/- 4.5) than did untreated fetuses--lung lecithin (5.35 micron per gram 1.23) and tracheal wash L/S (4.08 +/- 2.3). In contrast, phosphorylcholine glyceride… CONTINUE READING