Effect of maternal dexamethasone and alpha-ketoglutarate administration on skeletal development during the last three weeks of prenatal life in pigs.

@article{liwa2006EffectOM,
  title={Effect of maternal dexamethasone and alpha-ketoglutarate administration on skeletal development during the last three weeks of prenatal life in pigs.},
  author={Ewa Śliwa and Marcin R. Tatara and Henryk Nowakowski and Stefan Grzegorz Pierzynowski and Tadeusz Studziński},
  journal={The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians},
  year={2006},
  volume={19 8},
  pages={489-93}
}
BACKGROUND The effect of dexamethasone (Dex) on postnatal bone formation processes is known to decrease the synthesis of collagen and bone matrix, but the effect of alpha-ketoglutarate (AKG) is to induce positive effects on growth and skeletal development during postnatal life. However, the effects of Dex and AKG treatment on the prenatal processes of skeletal development have not been investigated so far. OBJECTIVE The aim of this study was to determine the effect of Dex and AKG administered… CONTINUE READING

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