Effect of matching of class I HLA alleles on clinical outcome after transplantation of hematopoietic stem cells from an unrelated donor. Japan Marrow Donor Program.

@article{Sasazuki1998EffectOM,
  title={Effect of matching of class I HLA alleles on clinical outcome after transplantation of hematopoietic stem cells from an unrelated donor. Japan Marrow Donor Program.},
  author={T. Sasazuki and T. Juji and Y. Morishima and N. Kinukawa and H. Kashiwabara and H. Inoko and T. Yoshida and A. Kimura and T. Akaza and N. Kamikawaji and Y. Kodera and F. Takaku},
  journal={The New England journal of medicine},
  year={1998},
  volume={339 17},
  pages={
          1177-85
        }
}
BACKGROUND The requirements with respect to HLA compatibility and the relative importance of matching for individual class I and class II HLA alleles in the transplantation of hematopoietic stem cells from unrelated donors have not yet been established. METHODS We performed retrospective DNA typing of alleles at 11 polymorphic loci of HLA genes in 440 recipients of hematopoietic stem cells from unrelated donors who were serologically identical with their respective recipients for HLA-A, B… Expand
HLA matching in allogeneic stem cell transplantation
HLA Association with hematopoietic stem cell transplantation outcome: the number of mismatches at HLA-A, -B, -C, -DRB1, or -DQB1 is strongly associated with overall survival.
  • P. Loiseau, M. Busson, +21 authors C. Raffoux
  • Medicine
  • Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
  • 2007
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