Effect of magnesium sulfate on maternal and fetal hemodynamics and fetal brain function and metabolism.


The hemodynamic effects, brain function, and metabolism of magnesium sulfate (MgSO4) were studied in seven fetal sheep experiments at 139 +/- 1.3 SE days of gestation. MgSO4 was intravenously infused to six gross-bred pregnant ewes at a rate of 4 gm/4 minutes as a loading dose, and 1.5 gm/60 minutes as a maintenance dose. There were no significant changes… (More)


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