Effect of lysophosphatidic acid on the ovum transport in mouse oviducts.

  title={Effect of lysophosphatidic acid on the ovum transport in mouse oviducts.},
  author={Kenji Kunikata and Shuji Yamano and Akira Tokumura and Toshihiro Aono},
  journal={Life sciences},
  volume={65 8},
The effects of lysophosphatidic acid (LPA) on ovum transport in mouse oviducts were studied. When excised oviducts were incubated at 37 degrees C under 5% CO2 in humidified air for 24 hours, addition of LPA at 10 microM to the medium significantly accelerated the rate of ovum transport, and 1 microM LPA slightly increased the ovum transport rate. These increases were not inhibited by 10 microM indomethacin, a cyclooxygense inhibitor, but were suppressed by 260 ng/ml of pertussis toxin or 10… CONTINUE READING


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